BEHAVIORAL NEUROSCIENCE
Tailored Protocols & Expert Insights for Your
In Vivo Preclinical Research
We help you maximize productivity and minimize expenses through collaboration, customized protocols, and optimized study designs.
So you can focus on your core research while receiving expert preclinical testing and data analysis.
We Offer a Comprehensive Library of
Behavioral Pharmacology Models
Neurodegeneration
Neurodegenerative diseases often result in cognitive, motor, and behavioral impairments. Rodent models allow researchers to study these behavioral changes and assess how potential treatments influence them.
This is particularly important for diseases like Parkinson’s and Huntington’s, which exhibit motor and cognitive deficits.
This is particularly important for diseases like Parkinson’s and Huntington’s, which exhibit motor and cognitive deficits.
Anxiety
Anxiety preclinical rodent models are used in scientific research to study and better understand the underlying mechanisms, causes, and potential treatments for anxiety-related disorders in humans. These models involve inducing or observing anxiety-like behaviors in rodents, typically mice or rats, to simulate aspects of human anxiety disorders.
The goal is to gain insights into the biological, genetic, neurochemical, and environmental factors contributing to anxiety and to test the efficacy of potential therapeutic interventions.
The goal is to gain insights into the biological, genetic, neurochemical, and environmental factors contributing to anxiety and to test the efficacy of potential therapeutic interventions.
Cognition & Motivation
Cognition and motivation are complex psychological processes that researchers often study using preclinical rodent models to gain insights into human behavior, neurological conditions, and potential therapeutic interventions.
These models provide a controlled environment for studying various aspects of cognition and motivation, allowing researchers to manipulate variables and observe behavioral responses.
These models provide a controlled environment for studying various aspects of cognition and motivation, allowing researchers to manipulate variables and observe behavioral responses.
Drug Abuse Liability
Drug abuse liability preclinical rodent models are used in research to study the potential for a substance to be abused or lead to addiction-like behaviors in humans.
These models help researchers understand the underlying mechanisms of substance abuse, evaluate the addictive properties of different drugs, and develop strategies for preventing and treating substance abuse disorders.
These models help researchers understand the underlying mechanisms of substance abuse, evaluate the addictive properties of different drugs, and develop strategies for preventing and treating substance abuse disorders.
Motor Function
Motor function preclinical rodent models are used in scientific research to study various aspects of motor function, neurological disorders, and the effects of potential therapies or interventions. These models involve rodents (typically mice or rats) that have been genetically modified, subjected to surgical procedures, or exposed to specific treatments to mimic certain aspects of human motor function or neurological conditions.
These models allow researchers to gain insights into the underlying mechanisms of motor control and test potential treatments and therapies for motor-related disorders.
These models allow researchers to gain insights into the underlying mechanisms of motor control and test potential treatments and therapies for motor-related disorders.
Pain
Preclinical rodent models are commonly used in biomedical research to study various aspects of pain and develop a better understanding of its underlying mechanisms.
These models serve as valuable tools for investigating pain-related processes, testing potential analgesic (pain-relieving) therapies, and advancing our knowledge of pain physiology.
These models serve as valuable tools for investigating pain-related processes, testing potential analgesic (pain-relieving) therapies, and advancing our knowledge of pain physiology.
Depression
Depression preclinical rodent models are used in scientific research to study various aspects of depression, including its underlying neurobiology, potential causes, mechanisms, and the development of new treatment strategies.
These animal models serve as tools to mimic certain aspects of depression-like behavior and physiological changes observed in humans. While these models can’t fully replicate the complexity of human depression, they provide valuable insights into the condition and its potential treatments.
These animal models serve as tools to mimic certain aspects of depression-like behavior and physiological changes observed in humans. While these models can’t fully replicate the complexity of human depression, they provide valuable insights into the condition and its potential treatments.
Schizophrenia
Schizophrenia preclinical rodent models are used in scientific research to study various aspects of schizophrenia, a complex and severe mental disorder that affects cognition, emotion, and behavior.
These rodent models aim to replicate certain behavioral, cognitive, and neurobiological features of schizophrenia in order to better understand its underlying mechanisms, test potential treatments, and explore novel interventions.
These rodent models aim to replicate certain behavioral, cognitive, and neurobiological features of schizophrenia in order to better understand its underlying mechanisms, test potential treatments, and explore novel interventions.
Behavioral Screening
Services can be designed to meet your project requirements, including customized equipment, protocols, and study validation support for your specific behavioral research needs.
Hippocampal Neuron Cultures
Hippocampal neurons isolated from mice or rats and grown in culture are commonly used in drug discovery as a screening platform or to model diseases of the central nervous system. Dissociated cultured neurons, grown in 96-well plates, can serve as a screening tool for drugs that are neuroprotective, or to establish cell-selective drug uptake and toxicity limits. Organotypic hippocampal slice cultures preserve much of the architecture and synaptic connectivity of the hippocampus, providing the simplicity of an in vitro system that models complex processes such as neuroplasticity, inflammation, and neurodevelopment.
Cochlear Cultures
Cochlear tissues, isolated from mice or rats and grown in culture, provide a research and screening tool for therapies addressing hearing loss and other disorders of the inner ear. Dissociated cochlear neurons are grown in 96-well plates and enable evaluation of treatments that support cochlear neuron survival and dendritic outgrowth. Organotypic cochlear explants are intact cochleae that are grown in culture. They are an ideal screening tool for drugs that target cochlear hair cells, neurons, or other support cells of the inner ear. Cochlear explants are commonly used for evaluating therapies that address ototoxic hearing loss (i.e., gentamycin or cisplatin-induced hearing loss) or to establish tropism of AAV gene therapies.
Additional Laboratory Services
- Pharmacokinetic Studies: Detailed analysis of substance absorption, distribution, metabolism, and excretion.
- Intricate Procedures: These include brain cannula implantation, site-specific brain injections, cerebral spinal fluid removal, brain region extraction, and more services upon request.
- Vivarium Services: Providing housing for rodents to support your research needs.
- Behavioral Screening: Leverage comprehensive automated screening services, the specifics of which can be customized to your project requirements.
Here’s How We Make Our Laboratory
Feel Like an Extension of Your Laboratory…
Individualized Attention
Direct engagement with our Ph.D.-level scientists for personalized attention in protocol design, adaptive study execution, and efficient problem-solving.
Collaborative Spirit
We see ourselves as an extension of your lab, ensuring open lines of communication and fast turnarounds. We believe in the power of shared knowledge and co-creation.
Adaptive Approach
Our smaller research lab emphasizes the quality and reproducibility of data over quantity. We have the flexibility to quickly adjust study designs during ongoing studies to optimize outcomes.
Access to Real-time Data
Transparency is at the heart of our work. You’ll have immediate access to raw data, helping you stay informed and make timely decisions.
Regulatory Compliance
With accreditation from multiple regulatory bodies, including the US National Institutes of Health, we maintain the highest scientific and ethical standards in accordance with guidelines for the humane care and use of laboratory animals.
Experience the difference a dedicated research partner makes!
We look forward to working with you on a customized testing model
Certified for
Grant-Funded Research
- Behavioral Pharma's NIH OLAW Assurance and Institutional Animal Care and Use Committee (IACUC) ensure ethical animal research. At the same time, our NIH Assurance number facilitates seamless collaboration with NIH-funded partners, expediting the approval process for grant-related projects.
- Our DEA Schedule I-V license allows comprehensive research across controlled substances, enabling a wide range of potential studies.
- These certifications assure the highest scientific standards and streamline your grant application process, letting you focus on your neuroscience research.